BIOLOGIA MOLECOLARE DELL'EMOSTASI


Biochimica

 

DOCENTE: Prof. Bernardi Francesco

 

 

Programma:

Protein Structure and Function Amino Acids Primary Structure: Peptide Bonds Secondary Structure: Alpha Helix, the Beta Sheet, and Turns and LoopsTertiary Structure: Nonpolar CoresQuaternary Structure Multisubunit StructuresThe Amino Acid Sequence of a Protein Determines Its Three-Dimensional Structure Exploring ProteinsThe Purification of Proteins Edman Degradation Basic concepts of chromatography Immunology Techniques ELISA Western Blot Electrophoresis- Enzymes: Basic Concepts and KineticsSpecific Catalysts Free Energy Transition State The Michaelis-Menten Model Vmax and KM Double-Reciprocal PlotsEnzymes Can Be Inhibited by Specific Molecules Vitamins and Coenzymes Catalytic and Regulatory StrategiesProteases: Activation by Specific Proteolytic CleavageHemoglobin Oxygen Transport Binding CooperativityIsozymes Covalent Modification Glycoproteins Lectins Metabolism: Basic Concepts and DesignThe Integration of MetabolismGlycolysis and Gluconeogenesis Gluconeogenesis and Glycolysis Are Reciprocally RegulatedThe Citric Acid Cycle Biosynthetic PrecursorsOxidative Phosphorylation The Respiratory Complexes Proton Gradients The Pentose Phosphate Pathway Protection Against Reactive Oxygen SpeciesGlycogen Metabolism Allosteric regulationFatty Acid Metabolism Fatty Acids Are Synthesized and Degraded by Different PathwaysProtein Turnover and Amino Acid CatabolismProteins Are Degraded to Amino Acids Ammonium Ion Is Converted Into Urea

Testi consigliati:

Biochimica. Berg, Jeremy M.; Tymoczko, John L.; and Stryer, Lubert.

 



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